Pre-filled plasma half-life model for Hexarelin. See how a 1 hour half-life affects steady state, accumulation, peak-trough swing, and clearance timing.
Preset values: 100 mcg every 12 hours, half-life ~1 hour.
~1h half-life. Tachyphylaxis is common; short courses are typical.
Open interactive chart →The half-life used here (1 hour) is the published or well-established estimate for Hexarelin from pharmacokinetic studies. The default dose (100 mcg) and cadence (every 12 hours) reflect typical standard protocols — not a prescription or recommendation. Your specific product's label and your clinician's protocol override any default here.
Accumulation. With a half-life of 1 hour and dosing every 12 hours, the ratio τ/t½ = 12.00 gives an accumulation factor of ~1.00×. That means the steady-state peak plasma mass is about 1.0× the mass of a single dose.
Time to steady state. Approximately 5 half-lives (~0.2 days) of consistent dosing before average concentration stops rising. Dose-escalation protocols that change doses before this point are titrating against a still-rising baseline, which is one reason weekly peptides feel "slow" at the start.
After a single dose, half of the Hexarelin is gone in about 1 hours, 97% is cleared in about 5.1 hours (five half-lives), and under 1% remains after about 6.6 hours.
| Cleared | Remaining | Half-lives | Time after one Hexarelin dose |
|---|---|---|---|
| 50% | 50% | 1 | 1 hours |
| 75% | 25% | 2 | 2 hours |
| 90% | 10% | 3.3 | 3.3 hours |
| 97% | 3% | 5.1 | 5.1 hours |
| 99% | 1% | 6.6 | 6.6 hours |
Between doses. At every 12 hours, doses land 12.00 half-lives apart, so about <0.1% of the peak is still present when the next dose goes in. The steady-state swing in this model runs from ~100 mcg at peak to ~<0.1 mcg at trough — a pulse that mostly clears before the next injection, so Hexarelin does not build up much at this cadence.
A first-order, one-compartment model: it leaves out absorption delay from the injection depot, protein binding and individual differences in clearance, and effects can outlast plasma levels. Good for dosing rhythm; not clinical pharmacokinetics.
This chart uses an estimated Hexarelin plasma half-life of about 1 hour. Published values can vary by formulation, route, assay, and study design.
A simple first-order model reaches practical steady state after about five half-lives, which is roughly 5 hours for Hexarelin.
After a single dose, half of the Hexarelin is gone in about 1 hours, 97% is cleared in about 5.1 hours (five half-lives), and under 1% remains after about 6.6 hours. Those are plasma estimates from a half-life of 1 hour; effects can outlast plasma levels, and detection windows depend on the assay.
Dosing every 12 hours is 12.00 half-lives apart, so about <0.1% of the peak level remains at the next dose. At steady state that means a peak of ~100 mcg and a trough of ~<0.1 mcg in the model.
No. It visualizes half-life, accumulation, peaks, and troughs from values you enter. It is not a prescription, dose recommendation, or substitute for the product label or clinician guidance.
Steady state explains why long-half-life compounds can keep rising for weeks after starting or changing a dose, while short-half-life compounds behave more like brief pulses.
Half-life charts for related peptides: CJC-1295 (8 days), Ipamorelin (2 hours), MOD-GRF (1-29) (30 minutes), Tesamorelin (30 minutes).
Peptide Protocol logs every actual injection time and shows your real timeline — not a model. Side-effect tracking included.
Get the iPhone app →Educational use only. Nothing on this page constitutes medical advice. Pharmacokinetic parameters are published estimates; individual PK varies. Use label values and consult a clinician for any dosing decision.
Educational use only. Peptide Protocol is an informational tool. Nothing on this page constitutes medical advice. Many peptides are prescription-only or restricted in your jurisdiction. Always consult a licensed healthcare professional before injecting any compound.