TB-500 half-life and pharmacokinetics chart
Pre-filled plasma half-life model for TB-500. See how a 5 hours half-life affects steady state, accumulation, peak-trough swing, and clearance timing.
Preset values: 2000 mcg every 4 days, half-life ~5 hours.
Thymosin-β4 fragment has short plasma half-life but binds actin systemically; weekly or twice-weekly cadence typical.
Open interactive chart →Why these values?
The half-life used here (5 hours) is the published or well-established estimate for TB-500 from pharmacokinetic studies. The default dose (2000 mcg) and cadence (every 4 days) reflect typical standard protocols — not a prescription or recommendation. Your specific product's label and your clinician's protocol override any default here.
Accumulation. With a half-life of 5 hours and dosing every 4 days, the ratio τ/t½ = 16.80 gives an accumulation factor of ~1.00×. That means the steady-state peak plasma mass is about 1.0× the mass of a single dose.
Time to steady state. Approximately 5 half-lives (~1.0 days) of consistent dosing before average concentration stops rising. Dose-escalation protocols that change doses before this point are titrating against a still-rising baseline, which is one reason weekly peptides feel "slow" at the start.
How long does TB-500 stay in your system?
After a single dose, half of the TB-500 is gone in about 5 hours, 97% is cleared in about 25 hours (five half-lives), and under 1% remains after about 33 hours.
| Cleared | Remaining | Half-lives | Time after one TB-500 dose |
|---|---|---|---|
| 50% | 50% | 1 | 5 hours |
| 75% | 25% | 2 | 10 hours |
| 90% | 10% | 3.3 | 17 hours |
| 97% | 3% | 5.1 | 25 hours |
| 99% | 1% | 6.6 | 33 hours |
Between doses. At every 4 days, doses land 16.80 half-lives apart, so about <0.1% of the peak is still present when the next dose goes in. The steady-state swing in this model runs from ~2000 mcg at peak to ~<0.1 mcg at trough — a pulse that mostly clears before the next injection, so TB-500 does not build up much at this cadence.
A first-order, one-compartment model: it leaves out absorption delay from the injection depot, protein binding and individual differences in clearance, and effects can outlast plasma levels. Good for dosing rhythm; not clinical pharmacokinetics.
TB-500 half-life FAQ
What is the plasma half-life of TB-500?
This chart uses an estimated TB-500 plasma half-life of about 5 hours. Published values can vary by formulation, route, assay, and study design.
How long until TB-500 reaches steady state?
A simple first-order model reaches practical steady state after about five half-lives, which is roughly 1.0 days for TB-500.
How long does TB-500 stay in your system?
After a single dose, half of the TB-500 is gone in about 5 hours, 97% is cleared in about 25 hours (five half-lives), and under 1% remains after about 33 hours. Those are plasma estimates from a half-life of 5 hours; effects can outlast plasma levels, and detection windows depend on the assay.
How much TB-500 is left when the next dose is due?
Dosing every 4 days is 16.80 half-lives apart, so about <0.1% of the peak level remains at the next dose. At steady state that means a peak of ~2000 mcg and a trough of ~<0.1 mcg in the model.
Does this TB-500 pharmacokinetics chart recommend a dosing schedule?
No. It visualizes half-life, accumulation, peaks, and troughs from values you enter. It is not a prescription, dose recommendation, or substitute for the product label or clinician guidance.
Why does steady state matter for TB-500?
Steady state explains why long-half-life compounds can keep rising for weeks after starting or changing a dose, while short-half-life compounds behave more like brief pulses.
Related for TB-500
Half-life charts for related peptides: BPC-157 (4 hours), GHK-Cu (2 hours).
Track your real TB-500 protocol
Peptide Protocol logs every actual injection time and shows your real timeline — not a model. Side-effect tracking included.
Get the iPhone app →Educational use only. Nothing on this page constitutes medical advice. Pharmacokinetic parameters are published estimates; individual PK varies. Use label values and consult a clinician for any dosing decision.
Educational use only. Peptide Protocol is an informational tool. Nothing on this page constitutes medical advice. Many peptides are prescription-only or restricted in your jurisdiction. Always consult a licensed healthcare professional before injecting any compound.