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Tirzepatide peptide calculator

A 10 mg Tirzepatide vial mixed with 2 ml of bacteriostatic water holds 5 mg/ml. A 2.5 mg dose is 0.50 ml — 50 units on a U-100 insulin syringe — and the vial holds 4 doses of that size.

10 mg vial + 2 ml bacteriostatic water, 2.5 mg dose:
50units on a U-100 insulin syringe
= 0.50 ml per injection · concentration 5 mg/ml · 4 doses per vial
Change the vial, water or dose in the full calculator →

Tirzepatide dosage chart: units to draw

Units on a U-100 insulin syringe (100 units = 1 ml) for Tirzepatide doses from 2.5 mg to 10 mg, by how much bacteriostatic water is in a 10 mg vial. The highlighted row is the 2.5 mg dose used above.

Dose1 ml water
10 mg/ml
2 ml water
5 mg/ml
3 ml water
3.33 mg/ml
Doses per vial
2.5 mg25 u
0.25 ml
50 u
0.50 ml
75 u
0.75 ml
4
5 mg50 u
0.50 ml
100 u
1.00 ml
1.50 ml
over 100 u
2
7.5 mg75 u
0.75 ml
1.50 ml
over 100 u
2.25 ml
over 100 u
1
10 mg100 u
1.00 ml
2.00 ml
over 100 u
3.00 ml
over 100 u
1

A 50-unit draw fits a 0.5 ml insulin syringe (50-unit capacity) with 1-unit markings.

Unit math only, not a dosing recommendation. The dose range is what published protocols and trials describe; see the Tirzepatide guide for sources.

How to reconstitute Tirzepatide

  1. Wipe both vial stoppers with a fresh alcohol swab and let them dry.
  2. Draw 2 ml of bacteriostatic water into a syringe.
  3. Insert the needle at an angle into the Tirzepatide vial and let the water run slowly down the inner wall — do not inject directly onto the powder.
  4. Do not shake. Gently swirl the vial until the peptide fully dissolves.
  5. Storage for Tirzepatide: Lyophilized refrigerated preferred. Reconstituted: refrigerated 2–8 °C, use within 28 days.
  6. For a 2.5 mg dose, draw to the 50-unit mark (0.50 ml) on a U-100 insulin syringe.

About Tirzepatide

Tirzepatide is a synthetic dual incretin agonist activating both GIP and GLP-1 receptors. Clinical trials show weight loss and glycemic effects exceeding those of GLP-1-only agents.

Half-life: Approximately 5 days (once-weekly dosing)
Typical dose range: Titration: 2.5 mg → 5 mg → 7.5 mg → 10 mg → 12.5 mg → 15 mg weekly
Class: Dual GIP / GLP-1 receptor agonist
Regulatory status: FDA approved as Mounjaro (type 2 diabetes) and Zepbound (obesity). Compounded tirzepatide currently faces the same FDA scrutiny as semaglutide.

Read the full Tirzepatide guide → — mechanism, side effects, storage, regulatory status and citations. Or browse the whole peptide glossary.

Other tools for Tirzepatide

Calculators for related peptides: Retatrutide, Liraglutide, Semaglutide, Survodutide, AOD-9604.

Need a different unit or a different question? The peptide dose converter moves a dose between mcg, mg and IU, and the Tirzepatide half-life chart shows how concentration accumulates across a dosing cadence. Loading Tirzepatide into a reusable 3 ml pen instead of drawing it with a syringe? The peptide pen calculator turns the same vial into mcg per click and clicks to dial. All of them are listed on the free peptide tools page.

Tirzepatide calculator FAQ

Is this a Tirzepatide peptide calculator or a reconstitution calculator?

Both. This Tirzepatide calculator converts vial strength, bacteriostatic-water volume, and target dose into milliliters and insulin-syringe units. It does not recommend a medical dose.

How much bacteriostatic water for a 10 mg Tirzepatide vial?

This page is pre-filled with 2 ml of bacteriostatic water for a 10 mg Tirzepatide vial because that is a common research ratio. You can adjust the water amount in the full calculator.

How many units is a 2.5 mg Tirzepatide dose?

50 units on a U-100 insulin syringe, when a 10 mg vial is mixed with 2 ml of bacteriostatic water (5 mg/ml). That is 0.50 ml. With a different amount of water the unit count changes — the dose chart on this page lists 1 ml, 2 ml, 3 ml mixes.

How many doses are in a 10 mg Tirzepatide vial?

4 doses of 2.5 mg. The number of doses depends only on vial strength and dose size — adding more or less water changes the volume of each draw, not how many draws the vial holds.

Does this Tirzepatide dosage calculator give medical advice?

No. It only performs unit math. Dosing, titration, and whether Tirzepatide is appropriate are clinical decisions that should be made with a licensed healthcare professional.

Skip the math — let the app handle it

Peptide Protocol remembers your Tirzepatide vial, shows the units for every dose, tracks what is left, and rotates injection sites for you.

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Educational use only. Peptide Protocol is an informational tool. Nothing on this page constitutes medical advice. Many peptides are prescription-only or restricted in your jurisdiction. Always consult a licensed healthcare professional before injecting any compound.